ABSTRACT
We have surveyed the motor changes in rats subjected to sciatic nerve axotomy. The rats were divided into two groups, each one consisting of ten animals, which underwent the following intervention: The first group (control): healthy rats without any injuries and experimental group: rats with injured sciatic nerve without treatment. at 12 weeks, the L4 and L5 spinal cord segments were removed. We evaluated nerve function using muscle electromyography (EMG) activity and sciatic function index (SFI) simultaneously with histological spinal cord analyses by stereological methods at 12 week. After nerve injury presented gross locomotor deficits at week 12. We also found that the volume of the anterior horn of spinal cord and total number of motor neurons were decreased after nerve axotomy (p<0.05). In conjunction, these results indicate that peripheral nerve injuries have more severe consequences on hind limb motor output.
En este estudio se examinaron los cambios motores en ratas sometidas a axotomía del nervio ciático. Las ratas se dividieron en dos grupos diez animales. El primer grupo (control) eran ratas sanas sin lesiones, y el grupo experimental consistió en ratas con nervio ciático lesionado sin tratamiento. A las 12 semanas, los segmentos de la médula espinal L4 y L5 fueron removidos. Se evaluó la función nerviosa mediante electromiografía muscular (EMG) y el índice de función ciática (IFC), simultáneamente con análisis histológicos de la médula espinal mediante métodos estereológicos. A las 12 semanas de la lesión nerviosa presentó déficit locomotor grueso. Además, se observó que el volumen del asta anterior y el número total de neuronas motoras disminuyeron después de la axotomía nerviosa (P <0,05). En conjunto, estos resultados indican que las lesiones de los nervios periféricos determinan graves consecuencias de la función motora de los miembros posteriores.
Subject(s)
Animals , Male , Rats , Spinal Cord/physiopathology , Spinal Cord/pathology , Sciatic Nerve/physiology , Sciatic Nerve/injuries , Rats, Wistar , Axotomy , Electromyography , Anterior Horn CellsABSTRACT
El presente estudio surge del interés por analizar los cambios percibidos por personas con diversidad funcional motora adquirida en sus vidas cotidianas tras la adquisición de perros de servicio. La revisión de investigaciones internacionales sobre efectividad de la tenencia de estos animales, así como la revisión de las teorías del vínculo y de la biofilia proporcionan un primer acercamiento para comprender los posibles cambios. A partir de todo ello surge la pregunta: ¿Cómo perciben los cambios en sus vidas cotidianas las personas en estudio tras la obtención de perros de servicio otorgado por la corporación Bocalán Confiar? El estudio se visualiza desde el paradigma interpretativo y contempla la revisión teórica y fuentes directas a través de entrevistas semi-estructuradas, mediante las cuales se obtuvo una perspectiva personal acerca de la situación. Se analizaron los cambios desde nueve categorías: Actividades de la vida diaria, trabajo remunerado, tiempo libre, relaciones interpersonales, familia, accesibilidad, responsabilidad, seguridad y vínculo. Los hallazgos dejan en evidencia que la obtención del perro de servicio no sólo influye en independencia funcional, sino también en el ámbito emocional, social y familiar...
This study arises from the interest in analyzing the changes perceived by people with motor functional diversity acquired in their daily lives following the acquisition of service dogs. The revision of international research on effectiveness of tenure of these animals, as well as the revision of the theories on bonding and biophilia provides insight to understand the possible changes. From all this, the question arises: How do the people under study perceive the changes in their daily lives after obtaining service dogs by Bocalán Confiar Corporation? The study is visualized from the interpretive paradigm and provides the theoretical review and direct sources through semistructured interviews, by means of which a personal perspective on the situation was obtained. Changes were analyzed from nine categories: activities of daily living, paid work, free time, relationships, family, accessibility, accountability, security and link. Findings evidence that the obtainment of the service dog does not only influences functional independence, but also in the emotional, social and family field...
Subject(s)
Humans , Male , Adult , Female , Middle Aged , Activities of Daily Living , Dogs , Personal Autonomy , Disabled Persons/rehabilitation , Architectural Accessibility , Interpersonal Relations , Leisure Activities , Disabled Persons/psychologyABSTRACT
@#ObjectiveTo evaluate the effect of electromyography biofeedback on motor function in children with spastic hemiplegia. Methods40 children with spastic hemiplegia were divided into control group (n=20) and treatment group (n=20). Both groups received comprehensive rehabilitation treatment. The treatment group received electromyography biofeedback in addition. They were assessed with Gross Motor Functional Measure (GMFM-88) in D and E items before and after treatment. ResultsThe scores of GMFM-88 in both D and E items were significantly different (P<0.01) before and after treatment in both groups, and significantly different between the treatment group and control group (P<0.05) after treatment. ConclusionElectromyography biofeedback can improve the motor capacity in children with spastic hemiplegia.
ABSTRACT
Objective To explore the relationship between upper-extremity motor functional outcomes and the brain white matter integrity with diffusion tensor imaging (DTI). Methods Seventeen patients with moderate upper-extremity impairment were enrolled and were assessed with the Wolf Motor Function Test (WMFT) and the upper limb portion of the Fugl-Meyer (FM) motor assessment battery. The structural integrity of the posterior limb of the internal capsule (PLIC) was assessed through examining the fractional anisotropy (FA) asymmetry between the ipsilesional and contralesional PLIC. Linear regression analysis was performed with FA asymmetry and the upper limb FM scores, WMFT asymmetry, log WMFT and grip strength asymmetry. Results FA asymmetry was strongly related to FM score (R~2=0.655, P＜0.002), WMFT asymmetry score (R~2=0.649, P＜0.002), lg WMFT (R~2＜0.636, P=0.002) and the grip asymmetry score (R~2 =0.414, P=0.02), respectively. Conclusion The clinical motor function is closely related to the white matter integrity of the internal capsule in patients 3-9 months after stroke. DTI assessment of the relative degree of white matter integrity in the internal capsule may be an useful approach to interpret motor deficits in patients with upper limb motor dysfunction and predict the motor function recovery.
ABSTRACT
OBJECTIVE: This study is to investigate the prognosis of functional ambulation in each type of cerebral palsy (CP). METHOD: Medical records of 385 patients were retrospectively reviewed that visited outpatients department and were diagnosed as CP. Various information was surveyed including CP type, gestational age at birth, birth weight and associated problems such as mental retardation and seizure and gross motor functional status such as ambulational status and Gross Motor Functional Classification System (GMFCS). All of them were compared between each type. The influences of seizure and mental retardation on gross motor function were also investigated. RESULTS: Functional ambulation was achieved in 58.2% in overall. Inspecting in each type, 93.7% of spastic hemiplegia, 67.6% of spastic diplegia, 12.2% of spastic quadriplegia, 78.7% of dyskinetic type can ambulate functionally. Birth weight or gestational age had no independent influences on ambulation within each type. Seizure influenced negatively on ambulation of diplegic CPs with significance and mental retardation in diplegic CPs and quadriplegic CPs than any other type. CONCLUSION: Over the half of CP patients achieved functional ambulation. Hemiplegia and diplegia had good prognosis among all types. Seizure and mental retardation negatively affected ambulation function of CP patients, especially in diplegic CPs and quadriplegic CPs.
Subject(s)
Humans , Birth Weight , Cerebral Palsy , Classification , Gestational Age , Hemiplegia , Intellectual Disability , Medical Records , Outpatients , Parturition , Prognosis , Quadriplegia , Retrospective Studies , Seizures , WalkingABSTRACT
@#Both motor therapy and functional electrical stimulation was used to treat the patients with hemiplegia. In 43 patients 17 cerebral haemorrhages, 26 cerebral infarctions and 7 traumatic cerebral injuries and haematomas male 28, female 15,were included in our studies. Therapy began in 1 to 2 weeks after lesion in 23, 2 to 5 weeks in 14, 3 -4 months in 3,6 months in 1,8 months in 1 and 1 year in 1. The results were evaluated by Barthel Index before and after the treatment,increasing from 41.02 ±20.58 pretreatment to 85.70±16.46 post-treatment with 22.58±15.10 times
ABSTRACT
Objective The experiment was designed to investigate the effect of acellular nerve allografts on the functional recovery and reconstruction of the nerve-muscle structure of the sciatic nerve defect in rats. Methods Acellular nerve allograft was transferred into the defected rat sciatic nerve with 10mm long.The wet weight of tibialis anterior was weighed at 12 and 24 weeks postoperatively compared with control group.The conducted velocity of regenerated nerve and the effect of regenerated nerve on tibialis anterior were investigated by electrophysiologic test,and silver staining combined with AChE histochemical methods were used in the experiment separately. Results The wet weight of tibialis anterior and the conducted velocity of regenerated nerve in experimental group were similar to those in control group in 12 and 24 weeks after transplantation.The positive acetylcholinesterase(AChE)histochemical reaction was observed in the tibialis anterior at 12 weeks with deeper staining and located in the middle of tibialis anterior tidily at 24 weeks after operation.The regenerated nerve bundles and nerve terminals were found to grow into the motor end-plate of the tibialis anterior in silver staining combined with AChE staining in experiment group.Electromyogram showed that the regenerated nerve has innervated tibialis anterior already.Conclusion The results indicated that extracted nerve allografts as a bridge can promote the motor functional recovery and reconstruction of the nerve-muscle structure of the defected rat sciatic nerve.